Prepare the beef: In a large bowl, combine the ground beef, salt, black pepper, garlic powder, onion powder, and Worcestershire sauce. Mix gently with your hands until just combined—avoid overmixing to keep the burgers tender.

Shape the patties: Divide the mixture into 4 equal portions. Gently form each portion into a patty about 3/4-inch thick. Press a slight dimple in the center of each patty to prevent bulging while cooking.

Preheat the grill or pan: Heat a grill or skillet over medium-high heat. If using a pan, add a small amount of oil to prevent sticking.

Cook the burgers: Place the patties on the grill or pan. Cook for about 4-5 minutes per side for medium doneness (adjust time for preferred doneness). Avoid pressing down on the patties to retain juices.

Add cheese (optional): If using cheese, place a slice on each patty during the last minute of cooking and cover to melt.

Toast the buns: Lightly toast the hamburger buns on the grill or in a toaster for added texture.

Assemble the burgers: Place each patty on a bun and add desired toppings. Serve immediately.